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Captopril is an oral drug and a member of a class of drugs called angiotensin converting enzyme (ACE) inhibitors. ACE inhibitors are used for treating high blood pressure, heart failure, and for preventing kidney failure due to high blood pressure and diabetes. Other ACE inhibitors include enalapril (Vasotec), quinapril (Accupril), ramipril (Altace), fosinopril (Monopril), benazepril (Lotensin), lisinopril (Zestril, Prinivil), moexipril (Univasc) and trandolapril (Mavik).
Captopril is used alone or in combination with other drugs for the treatment of high blood pressure and heart failure. Captopril also is used for improving survival and preventing heart failure and hospitalizations for heart failure after a heart attack. Like other ACE inhibitors, captopril may slow the progression of kidney failure in patients with diabetes or high blood pressure. It is used for preventing nephropathy (kidney disease) caused by diabetes and high blood pressure.